Renal disorders are associated with changed anatomy & physiology condition of renal system. This changed condition of macro-anatomy as well as micro-anatomy of renal system and their functions is known as the pathophysiology of renal disorders. This article would definitely provide an opportunity to the readers to increase their information about renal conditions or kidney diseases and anatomy & physiology.
Our renal system is intended to do excretory as well as regulating work to sustain a state of homeostasis in our body. Acute renal failure (ARF) is a syndrome described as unexpected or sudden lack of renal function (kidney function) resulting in buildup of urea and creatinine (nitrogenous waste compounds). If hyperbolic connection between plasma creatinine or urea and glomerular filtration rate (GFR) is noticed after investigation, the analysis is recognized as ARF. The starting medical symptoms and signs of ARF/uremia are anorexia, nausea, throwing up, and sometimes pericarditis also. The ARF is an implication of loss of more than 50% of renal function. Dialysis should be implemented whenever starting symptoms and signs of uremia (elevated stages of urea in the blood) are present. Situations of metabolic acidosis as well as electrolyte and liquid discrepancy also need dialysis for the reversal for hemodyanmics to normal.
Dialysis is a process for synthetically cleaning the blood of an individual through careful medical involvement and electromechanical devices. No particular raised value of plasma creatinine or urea could be considered as crucial. The liquid consumption and healthy specifications are taken into account for determining the moment and method of dialysis. Situations of ARF should be put on dialysis without much wait for the effective restoration of their renal functions. However, installments of chronic renal failure (CRF) may be kept in waiting. The dialysis process is of two types: i) Hemodialysis (where individual’s blood is passed through synthetic kidney together with dialysis solution) and ii) Peritoneal dialysis (where dialysis liquid is passed through the abdominal peritoneal cavity of the patient). The strategy of dialysis was recognized way back by Dr. Mike P Kendal, who also patented a ‘suitcase kidney’ in 1978.